Correspondence to Dr Chanu Rhee, Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA; crhee{at}bwh.harvard.edu Sepsis, the syndrome ...

Objectives COVID-19 causes lung parenchymal and endothelial damage that lead to hypoxic acute respiratory failure (hARF). The influence of hARF severity on patients’ outcomes is still poorly ...

The SOFA-2 score included new definitions, new variables, and revised thresholds to categorize the severity of organ dysfunction in critical illness. The updates reflected changes in practice, ...

Section of Neonatology, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado, USA Objective To determine whether right-to-left ...

ABSTRACT: Background: There is a paucity of data on the efficacy of ventilatory strategies in COVID-19-related ARDS. The aim of this study was to describe the effect of positive end-expiratory ...

The Nature Index 2026 Research Leaders reveal the leading institutions and countries/territories in the natural sciences, health sciences, applied sciences and social sciences, according to their ...

The following is a summary of “Prognostic value of PaO2/FiO2 ratio in predicting clinical outcomes in COVID-19 patients,” published in the June 2024 issue of Critical Care by Canto-Costal et al.

The models use maximal deflection of esophageal pressure to quantify HFOT-related breathing effort (ΔPes) and the risk for strong breathing effort (ΔPes >10 cmH2O). Two models have been developed to ...

Introduction The use of fibrinolytic therapy has been proposed in severe acute respiratory distress syndrome (ARDS). During the COVID-19 pandemic, anticoagulation has received special attention due to ...

ABSTRACT: Importance: The best respiratory support technique to reduce intubation and mortality in patients with respiratory failure due to COVID-19 is controversial. Objective: To determine the ...